If you have an underactive thyroid gland. If you are taking other medicines, including those available to buy without a prescription, as well as herbal or complementary medicines. Try to keep your regular appointments with your doctor. Accessed Sept. 7, 2022. You may report side effects to the FDA at 1-800-FDA-1088. 2010; doi:10.1016/j.jacc.2009.07.074. Classes: Nitrates, Angina Print Dosing & Uses AdultPediatricGeriatric Dosage Forms & Strengths tablet 10mg 20mg. Keep all medicines out of the reach and sight of children. Accessed Sept. 7, 2022. These side effects may go away during treatment as your body adjusts to the medicine. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Less commonAbnormal heart soundabsence of or decrease in body movementarm, back, or jaw painblack, tarry stoolsbladder painbleeding after defecationbleeding gumsblood in the urine or stoolsblurred visionbody aches or painburning while urinatingburning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelingschest pain or discomfortchest tightness or heavinesschillscold sweatscoldsconfusionconvulsionscough or hoarsenessdecreased urinediarrheadifficult or labored breathingdifficult, burning, or painful urinationdilated neck veinsdizzinessdizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting positiondry mouthear congestionextra heartbeatsfaintingfast, slow, irregular, pounding, or racing heartbeat or pulsefever or chillsflu-like symptomsfrequent urge to urinatefrequent urinationgeneral feeling of discomfort or illnessheadacheheadache, severe and throbbingheart murmurincreased need to urinateincreased sweatingincreased thirstincreased volume of pale, dilute urineirregular breathingitching, pain, redness, or swelling on the legjoint pain, stiffness, or swellinglightheadednessloss of appetiteloss of voicelower back, side, or stomach painmuscle aches and painsmuscle crampsnasal congestionnausea or vomitingnervousnessnumbness or tingling in the hands, feet, or lipspain or discomfort in the arms, jaw, back, or neckpain, tension, and weakness upon walking that subsides during periods of restpartial or slight paralysispassing urine more oftenpinpoint red or purple spots on the skinpounding in the earsrunny noseshakiness in the legs, arms, hands, or feetshiveringsneezingsore on the legsore throatsudden decrease in the amount of urinesweatingswellingswelling of the face, fingers, feet, or lower legstightness in the chesttrembling or shaking of the hands or feettrouble sleepingtroubled breathinguncomfortable swelling around the anusunusual bleeding or bruisingunusual tiredness or weaknessvomiting of blood or material that looks like coffee groundsweaknessweight gainRareBluish-colored lips, fingernails, or palmsdark urinepale skinrapid heart rateGet emergency help immediately if any of the following symptoms of overdose occur:Symptoms of overdoseBlurred or loss of visionbulging soft spot on the head of an infantchange in consciousnesschange in the ability to see colors, especially blue or yellowcold, clammy skindisturbed color perceptiondouble visionfeeling of constant movement of self or surroundingshalos around lightsheadache, severe and throbbingloss of consciousnessnight blindnessoverbright appearance of lightsparalysissensation of spinningtunnel visionSome side effects may occur that usually do not need medical attention. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. The table below contains some of the most common ones associated with isosorbide mononitrate. Instead, the best way to dispose of your medication is through a medicine take-back program. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Isosorbide mononitrate belongs to the group of medicines called nitrates. Isosorbide mononitrate (Monoket) is available as a generic medication and may be significantly cheaper compared to the brand version. If you notice any other effects, check with your healthcare professional. It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. https://naturalmedicines.therapeuticresearch.com. Can isosorbide mononitrate cause problems? Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). Select a condition to view a list of medication options. This document does not contain all possible drug interactions. It will not treat an angina attack that has already begun. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Natural Medicines. Danshen. Mayo Clinic. information highlighted below and resubmit the form. Includes Isosorbide Mononitrate indications, dosage/administration, pharmacology, mechanism/onset/duration of action, half-life, dosage forms, interactions, warnings, adverse reactions, off-label uses and more. Almost 70% of older adults use them. These products are provided 'AS IS' and 'as available' for use, without warranties of any kind, either express or implied. https://naturalmedicines.therapeuticresearch.com. Patients were randomized to either 60 mg 5-ISMN once daily (od) for two weeks or to 30 mg 5-ISMN od for one week followed by 60 mg 5-ISMN od for one week. For haemoglobin formation vit. Isosorbide mononitrate (Monoket) may interact with certain medications or supplements. it is a safe and effective alternative; the choice between beta blockers and calcium channel blockers depends . Do not double the dose to catch up. Do not stop taking isosorbide without talking to your doctor. Nitrates | Prescribing information | Angina | CKS | NICE Ginkgo. Do not keep out-of-date or unwanted medicines. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Talk to your doctor about the possible risks of using this medication for your condition. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Your provider might temporarily have you stop isosorbide mononitrate (Monoket) if this happens. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. Accessed Sept. 7, 2022. Isosorbide mononitrate (Monoket): Basics, Side Effects & Reviews - GoodRx 88 ratings on Drugs.com. Registered in England and Wales. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. My cardiologist recommended I get on metropolol. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. I strongly feel that there is coronary ischemia. It can cause your blood pressure to become dangerously low. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Vascular dilatation can precipitate venous pooling with decreased return to the heart, hypotension and reflex tachycardia. Copyright, 2023. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. By signing up, I agree to GoodRx's Terms and Privacy Policy, and to receive marketing messages from GoodRx. Accessed Sept. 7, 2022. Unless there is a specific reason you need the brand, the generic medication will be a better value. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Many people using this medication do not have serious side effects. Integrative medicine (complementary and alternative medicine). There are no data on passage of isosorbide mononitrate in human milk, but some excretion seems likely. This medication belongs to a class of drugs known as. This content does not have an Arabic version. Your health care provider and pharmacist can help you stay away from unsafe interactions. Take the missed dose as soon as you remember it. Store at room temperature away from light and moisture. Accessed Sept. 7, 2022. You need to take it every day in order for it to work. Never give it to other people even if their condition appears to be the same as yours. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Whenever you take more than one medicine, or mix it with certain foods or beverages, you"re at risk of a drug interaction. Isosorbide mononitrate (Monoket) works slowly to help prevent chest pain. The most common side-effect is headache. Does Alcohol Raise Your Blood Pressure? Isosorbide mononitrate is a nitrate-class drug used for the prophylactic treatment of angina pectoris; that is, it is taken in order to prevent or at least reduce the occurrence of angina. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. you should know that isosorbide may cause dizziness, lightheadedness, and fainting when you get up too quickly from a lying position, or at any time, especially if you have been drinking alcoholic beverages. Minimally clinically significant. Some products have ingredients that could worsen your heart failure. Let your provider know if they are excessive. https://naturalmedicines.therapeuticresearch.com. Older adults may be more sensitive to the side effects of this medication, especially dizziness and lightheadedness, which could increase the risk of falls. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Then, there was a two-week placebo washout, after which the alternative treatment was given. Compare a few possible alternatives below. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . It can make you really dizzy. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). Modified-release nitrate preparations: use a once-daily dose to maintain a nitrate-low period and thus minimize tolerance. But only about 25% of people who take herbal supplements tell their health care providers. Theyre fast, easy-to-use and free! Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. Isosorbide mononitrate 30% immediate-release 70% sustained-release formulation: a review. 2023 Lybrate, Inc. All rights reserved. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Please note that only the generic name of each medication is listed below. All rights reserved. Consult your doctor for more details. Aspirin has an average rating of List of Antianginal agents (antianginal drugs) - Drugs.com It works to relax your blood vessels. It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. http://www.upandaway.org. This medicine is for you. https://naturalmedicines.therapeuticresearch.com. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. If you have ever had an allergic reaction to a medicine. Keep this medication in the container it came in, tightly closed, and out of reach of children. Some of these interactions can be life-threatening. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. We comply with the HONcode standard for trustworthy health information. Take your next dose at the regular time. Each day, take the first dose when you wake up, then take the second dose 7 hours later. https://naturalmedicines.therapeuticresearch.com. This product is available in the following dosage forms: There is a problem with It can cause your blood pressure to become dangerously low. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. It does not have such side effects. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. May also be prescribed off label for Esophageal Spasm. Herbal medications in cardiovascular medicine. Taking erectile dysfunction medications or drinking alcohol while taking isosorbide mononitrate (Monoket) can cause your blood pressure to get dangerously low, which can be life-threatening. That's why you need to talk with your health care provider before you take herbal supplements if you take prescription medicines. If you have recently had a head injury or a heart attack. Consult your pharmacist or local waste disposal company. The authors assessed the occurrence of angina pectoris and headache by diary cards while taking into account the number of isosorbide dinitrate sublingual puffs and paracetamole tablets required. It is also important information to carry with you in case of emergencies. The longer you take isosorbide mononitrate, the more your body can become used to it (called tolerance), and then it can have less of an effect. Are you looking for information on isosorbide dinitrate (Isordil) instead? Cleophas TJ, Niemeyer MG, van Der Wall EE. You may report side effects to the FDA at 1-800-FDA-1088. Who should not take Isosorbide Mononitrate? (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. Available for Android and iOS devices. Methods: Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Disclaimer. Please upgrade your browser or download modern browsers from here! Browse Drugs and Medicines. Breastfeeding:There is data that nitrates are excreted in breast milk and may cause methemoglobinemia in infants. Isosorbide is in a class of medications called vasodilators. The extended-release tablet usually is taken once daily in the morning.